Lean AF by Iron Mag labs provides guaranteed absorption with no needles, no pills and no liver stress!
Although comparable to oral-dosage forms in efficacy, topical creams have numerous advantages over oral forms. First, topical administration avoids the first-pass effect of metabolism associated with the oral route. Therefore, topical administration allows for much higher and improved bioavailability. Second, topical administration allows prolonged release of prohormone compounds, which can improve adherence. Third, topical administration minimizes adverse effects due to lower prohormone peak concentrations. Prohormones are very effectively removed by the liver when taken orally. This means that much higher doses, ten to twenty times higher, must be taken when administering prohormones orally, as compared to topical administration that avoid the first pass effect of the liver.
Lean AF Ingredient Breakdown
19 Nor-DHEA is a naturally occurring DHEA isomer. The term “19 Nor” means that a methyl group was removed from testosterone at a key position on its molecular backbone. This slight alteration of the chemical structure reduces the DHT related side effects (prostate issues, balding, acne) as well as the estrogenic side effects (gyno, bloating) that testosterone possesses. Enanthated 19 Nor-DHEA or 3b-enanthoxy-19-nor-androst-4-ene-17-one is a new compound that is a two step precursor to 19 Nor-Testosterone.
Nor DHEA is the prohormone of choice for many people looking to improve their overall lean muscle mass. Prohormones are substances that get converted into hormones in the body that amplify the effects of the steroids already in your body. Prohormones like 19-Nor are the most powerful type of supplement you could take if you’re looking to increase testosterone and build muscle mass. Prohormones have been shown to cause great gains in strength and size, so you’ll feel stronger and have more endurance.
Nor-DHEA is a precursor to nandrolone and is known and identified by many names, including 19-Norandrostenedione, 17beta-Hydroxy 19 Nor 4 Androsten 3 One, Estrenolone, Nandrolone, Norandrostenolone, and Nortestosterone. Nandrolone is similar to testosterone in some ways, but it is six times more anabolic than testosterone which results in improved muscle mass. Chemically, the structure of 19-Nor-DHEA differs from testosterone in that it’s missing the number 19 carbon atom and the attached hydrogen atoms. The flatter three-dimensional chemical structure results in fewer side effects for prostate and other sexual tissues and improved skeletal muscle binding, which increases the desired effects. This means nandrolone has anabolic effects that take place in muscle, but fewer androgenic effects which occur in sexual tissues. Serious bodybuilders love nandrolone for its ability to bulk, create mass gains, cut, and increase energy, endurance, and recovery.
7-Keto DHEA (3-Acetyl-7-Oxo-Dehydroepiandrosterone), also known as 7-oxoprasterone, is a prohormone produced by metabolism of the prohormone dehydroepiandrosterone (DHEA). 7-Keto® DHEA is not directly converted to testosterone or estrogen, and has thus been investigated as a potentially more useful relative of DHEA.
When it comes to fat loss, one way in which cortisol causes problems is by blunting thyroid production. Not only does it lower overall thyroid output, but it inhibits the conversion of T4 to T3 (the more active form of the hormone). The end result is readily apparent in those who have undergone long-term corticosteroid therapy (prednisone, methylprednisone; both are corticosteroids like cortisol), as these patients frequently add bodyfat during treatment. Unfortunately, bodybuilders are exposed to many risk factors for increased cortisol levels, such as weight training, cardio, low-calorie dieting, low-carb dieting, and not getting enough sleep (under 7 hours/night has been shown increase production of this hormone). Even the disconnection of AAS can increase cortisol levels via cortisol rebound. Basically, anything which places stress on the body, either physical or emotional/mental, will cause levels of this hormone to rise.
7-Keto DHEA has been clinically proven to increase T3/T4 levels, as well as the conversion rate of T4 to T3 by directly inhibiting the production of cortisol in the body. It does this by competing with the hydroxysteroid dehydrogenase enzyme (11 b-HSD 1), which is responsible for converting cortisone into cortisol. In laymen’s terms, 7-keto uses up circulating 11 b-HSD 1, thereby leaving less of this enzyme available to initiate the conversion of cortisone to cortisol. However, unlike synthetic thyroid, it doesn’t suppress the hypothalamic pituitary thyroid axis, so natural thyroid production remains unaffected even after discontinuation. This, along with the fact that supplemental 7-Keto has not been shown to have any significant adverse side effects, eliminates the need for off-time/recovery time when using 7-Keto DHEA.
5-DHEA has been popular in the life extension crowd since the 1980’s. It’s typically used for its ability to support energy and general well being. More recently, higher doses of 5-DHEA have been used to improve body composition due to DHEA’s mild anabolic and thermogenic effects. This makes 5-DHEA an excellent choice for cutting during a calorie deficient diet, since 5-DHEA has good muscle sparing properties.
5-DHEA converts to testosterone at a rate of about 1%, however it has high conversion to 5-androstenediol, where it gets its mild androgenic and anabolic effects. 5-DHEA’s thermogenic properties come from its conversion to 7-OXO-DHEA.
Lean AF Topical Delivery System
- Dimethyl Isosorbide (DMI) – is a high purity solvent and carrier which offers a safe, effective delivery enhancement mechanism for the active ingredients in Lean AF.
- Ethoxydiglycol – is a cosmetic grade solvent that conforms to the current USP/NF monographs. Ethoxydiglycol is particularly appropriate for skin care preparations where it acts as an excellent solvent and carrier.
- Propylene glycol – is an organic compound that is used 2 primary reasons. First, it has the traits of a humectant; it is able to absorb and help the skin retain moisture. Second, it helps active ingredients penetrate the skin.
- Glycerin – when used on skin works as humectant, which is why it attracts moisture onto your skin.
- Carbomer – helps to distribute and suspend the active ingredients in the Lean AF.
- Triethanolamine (TEA) – Helps the water-soluble and oil-soluble ingredients blend better. TEA neutralizes fatty acids and solubilizes oils and other ingredients that are not completely soluble in water.
Suggested use for Lean AF
For best results apply 1 pump of LEAN AF Cream twice daily (1 pump in AM & 1 pump in PM) to the upper arms, shoulders/traps, thighs or abdominal areas. Ensure the areas are clean and free from excessive hair, avoid showering or swimming for at least 8 hours after application.