I-LOAD, short for “Insulin Load”, was designed to increase insulin sensitivity, and force carbohydrates, amino acids, creatine, and other anabolic nutrients into muscle tissue. Insulin is the most powerful anabolic hormone in your body that has the ability to increase protein synthesis, inhibit protein breakdown and transports glucose, amino acids and creatine into muscle tissue.
Almost every amateur and professional bodybuilder is familiar with the power of insulin due to the powerful glycogen pump it can produce along with hyper-loading of nutrients post workout. In addition, insulin also has a huge nutrient-partitioning effect, driving food (and stored food energy) into building muscle instead of building fat.
How important is Insulin for building muscle?
Insulin is the most powerful anabolic hormone in your body that has the ability to increase protein synthesis, inhibit protein breakdown and transports glucose, amino acids and creatine into muscle tissue. Almost every amateur and professional bodybuilder is familiar with the power of insulin due to the powerful glycogen pump it can produce along with hyper-loading of nutrients post workout.
In addition, insulin also has a huge nutrient-partitioning effect, driving food (and stored food energy) into building muscle instead of building fat. So the key here is to promote this powerful hormone without risking the dangerous side effects.
Why is Insulin sensitivity important?
One of the key elements to managing the power of insulin (and maintaining health), is to promote one’s insulin sensitivity. A person who is “insulin resistant” has a hard time processing carbohydrates and their body releases a ton of insulin to get glucose into the resistant cells. The key to supporting an efficient, healthy body is to promote insulin sensitivity where the body doesn’t have to release a ton of insulin to get the glucose into the cell. Insulin sensitivity is partly genetic and varies with each individual usually peaking highest in professionally trained athletes.
Three of the best ways to increase insulin sensitivity are through resistance training, cardiovascular training and manipulating one’s diet.(1)(2) A moderate carbohydrate diet rich in Omega-3 fatty acids, fish oil and fiber can make a dramatic impact upon one’s insulin sensitivity. On the flip side, the low-carbohydrate, high-fat diets that have become popular lately can decrease insulin sensitivity. People should be very careful of these types of diets and limit their use to a maximum of 3 weeks at a time especially if muscle gain is one’s preferred goal.
What are the benefits from supplementing with I-Load?
Force-Feed Muscle Hypertrophy
Carb Transport Facilitator
Hyperload Glucose and Amino Acids
Insane Muscle Pumps
I-LOAD™ is not your simple ALA/chromium combination. Utilizing cutting edge science, I-LOAD™ uses the following powerful weapons to help keep insulin sensitivity at its maximum and store nutrients like no other product currently on the market:
Banaba Leaf Extract promotes glucose transport from the blood into body cells.* Recently, researchers have isolated an active ingredient in the banaba leaf called corosolic acid, which was originally thought to be “the” blood sugar regulating substance in the leaf. A study published in the journal Planta Medica in 2001 compared a whole-leaf extract of banaba with insulin in cell cultures. The researchers surmised that the whole herb may have a glucose lowering effect.* In other animal studies, administration of banaba leaf extract promoted reduced weight gain and reduced adipose tissue, with no changes in diet.*
Originating from India, Gymnema Sylvestre is known as gur-mar, or “sugar destroyer.” Scientists think its active ingredients (gymnemic acids)help protect the cells of the pancreas from free radical damage, helping them to regenerate and produce insulin more effectively.* A recent Harvard study suggests that Gymnema may help maintain healthy blood sugar levels already in normal range.* At King’s College in London, a study surmised that Gymnema acts by supporting cell permeability, therefore reducing insulin resistance. Studies have suggested that gymnema may promote reduced glucose absorption from the intestine, lowering the amount of glucose available to be stored as fat.*
When gymnema leaf is placed directly on the tongue, it eliminates the sensation of sweetness. The leaves of Gymnema sylvestre perform two significant functions. First, they may help regulate blood glucose, especially after eating.* Secondly, they are insulin tropic and promote insulin secretion.* By this multi-pathway approach, Gymnema sylvestre may prove a valuable aid in hyper-loading glucose into muscles.*
Momordica 10:1 Extract
Bitter melon is the common name for Momordica charantia, also known as African cucumber, balsam pear and bitter gourd. The phytochemicals present in bitter melon suggest that there are multiple uses for this herb. Among the constituents in bitter melon, charantin is identified as an important agent that may help promote healthy blood-sugar levels already within normal range.*
In a study published in the journal Chemistry & Biology- March 2008, a research team, headed by Dr. Mon-Jia Tan of the Chinese Academy of Sciences in Shanghai, isolated and described several compounds from bitter melon known as cucurbitane triterpenoids, and tested their effects on glucose (sugar) and fat metabolism in cells and in mice. When tested in muscle and fat cells, the researchers found, the compounds stimulated the glucose receptor GLUT4 to move from the cell interior to the cell surface, thus promoting more effective glucose metabolism. Tests in mice of two of the compounds found that they promoted both glucose tolerance and fat burning, and one was particularly effective in promoting glucose tolerance in animals consuming high fat diets.*
Momordica has been suggested to be just as effective as glibenclamide in promoting healthy blood sugar levels already within normal range (J Ethnopharmacol 2003; 88(1): 107-111).* In fact, this was surmised by a large study at Harvard University Medical School (Care 2003; 26(4): 1277-1294).* It appears that mormodica contains compounds similar in structure to insulin, and which may be useful to athletes.* There is evidence that mormodica may promote the release of healthy glucose levels into the bloodstream from the liver (Am J Health Syst Pharm 2003; 60(4): 356-359).*
Chromium helps insulin transport sugar to the cells.* Chromium works to make insulin more effective by “bridging” insulin to cell membranes, thus promoting the number of active insulin receptors, resulting in increased insulin sensitivity.* The trace mineral chromium is found in skin, fat, muscle, brain and the adrenal glands. There is about 6 mg in each of us and it is important! Chromium absorption through the small intestine is very poor; so normally, a lot of it gets excreted in urine. Studies suggest that chromium supplementation may help promote healthy blood sugar levels already within normal range.*
There are various forms of chromium suitable for human ingestion. The Polynicotinate form of chromium called “Chromium polynicotinate” is the most absorbable.* Chromium polynicotinate is a unique molecule that binds chromium with niacin, a compound found in breast milk, which helps the body better absorb and process minerals.*
The Core Four
L-Carnitine: Responsible for the transport of fats into the cells to be used for energy in the body. By raising the level of muscle carnitine, you support the fat burning process, and because your body becomes more efficient at processing fuel, it will increase your energy levels. Elevating carnitine will also improve physical performance by burning more fat, sparing glycogen, clearing muscle lactate, and increasing anabolic hormone response.
Choline Bitartrate: The combination of caffeine, carnitine and choline supplementation decreases body fat and serum leptin concentration in rats, and increases fat utilization for energy. Leptin is a protein hormone that regulates energy intake and expenditure, including appetite and hunger, metabolism and behavior. Choline plays a role in the oxidation of fatty acids, carrying them out of the liver and to the mitochondria of skeletal muscle cells and other metabolically active tissue.
Green Coffee Bean: The chlorogenic acid found in unroasted green coffee beans has been shown to inhibit an enzyme, glucose-6-phosphatase, an enzyme involved in the release of sugar for energy use. By inhibiting the availability of glucose for energy, the body then is forced to turn to alternate sources of fuel, namely fats. The end result is safe and effective weight loss and a change in body composition by tricking your body into preferentially using fat as fuel.
ADILASE™: An exclusive specialized extract of Hemerocallis fulva, designed to maximize the release of fat from stubborn cells. ADILASE™ helps stimulate fat cells to release fat into the bloodstream. Many people struggle to lose fat with ‘typical’ high-stimulant fat burners due to a condition called lipolytic catecholamine resistance, which means that their fat cells do not readily release fat when stimulated to do so. When ADILASE™, is combined with caffeine, it improves the lipolytic (fat releasing) sensitivity in low-responding fat storage cells, indicating that the lipolysis-promoting activity of this combination may be beneficial for improving body fat metabolism.
The Diablo Inferno Complex
6AM™–Aframomum melegueta extract: A specialized extract of ‘Grains of Paradise’, the fat fighting potent seeds from Africa. Clinical trials exploring the weight loss benefits of 6AM™ found that it can significantly increase energy expenditure and loss of brown adipose (fat) tissue. One of the key ingredients involved in the thermogenic response is 6-paradol, a pungent aromatic ketone also found in ginger.
Evodiamine: A capsaicin-like alkaloid that acts as a vanilloid receptor agonist, without the peppery hot taste. Like capsaicin Evodiamine increases body heat production and raises resting core temperature, increasing the calories and fat that are burned for energy. The stimulant and appetite suppressant effects of evodiamine can be attributed to its effects on catecholamine levels. Evodiamine increases the release of catecholamines such as adrenaline and dopamine from the adrenal glands, increasing energy levels and decreasing appetite.
Pheneylethylamine HCI (PEA): A monoamine alkaloid that can improve mood, mental acuity, energy and focus. Although relatively short-lived, when combined with and MAO inhibitor, the effects can be prolonged. Part of sticking to a diet plan involves feeling good and staying motivated and PEA can help you keep a positive frame of mind.
Hordenine: Has been known as a central nervous stimulant that helps to aid in the effects of weight loss. It assists in the release of fat cells for energy and helps the process of slowing down food digestion, which in turn can make you feel fuller longer. It also acts as a mild MAO inhibitor, thereby prolonging the effects of monoamine alkaloids like PEA.
What dosage should I take?
As a dietary supplement, Take 1 capsule 30 to 45 minutes prior to exercise with 1 serving of KARBOLIC or 50 grams carbohydrates. Advanced users may take 2 capsules with at least 2 servings of KARBOLIC or 100 grams of carbohydrates.
Not for use by individuals under the age of 18 years. Do not use if pregnant or nursing. Keep out of the reach of children. Do not consume this product if you have a medical condition and/or taking any prescription medication. Do not exceed recommended servings. Do not use this product if you are at risk or are being treated for high blood pressure, kidney, thyroid or psychiatric disease, anxiety, depression, seizure, enlarged prostate or stroke. Before beginning any supplement or training program always consult a physician first.
*”These statements have not been evaluated by the Food & Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease. ALWAYS consult your physician before taking supplements.”
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