Gear Cream by Iron Mag labs provides guaranteed absorption with no needles, no pills and no liver stress!
Although comparable to oral-dosage forms in efficacy, topical creams have numerous advantages over oral forms. First, topical administration avoids the first-pass effect of metabolism associated with the oral route. Therefore, topical administration allows for much higher and improved bioavailability. Second, topical administration allows prolonged release of prohormone compounds, which can improve adherence. Third, topical administration minimizes adverse effects due to lower prohormone peak concentrations. Prohormones are very effectively removed by the liver when taken orally. This means that much higher doses, ten to twenty times higher, must be taken when administering prohormones orally, as compared to topical administration that avoid the first pass effect of the liver.
Gear Cream Ingredient Breakdown
4-DHEA is a naturally occurring DHEA isomer. It’s structure closely resembles regular DHEA but the double bond in the 4th position dramatically changes its effects. 4-DHEA is also expected to have a higher conversion rate to testosterone compared to regular DHEA. The 4-DHEA also lacks the calorie burning thermogenic properties, therefore offering superior calorie retention for a bulking effect. This increased anabolic potency and reduced thermogenic action will lead to noticeable gains in strength, lean tissue growth, and weight gain.
4-DHEA is both very anabolic and androgenic. Users report to experience tremendous increases in muscle mass with quickly followed strength gains. The elevated testosterone levels will increase red blood cell count and produce what users refer to as “skin bursting pumps”. The elevated hormone levels will also increase protein synthesis, which will increase recovery times. Be sure to eat 1.5-2 grams of protein per body weight. 4-AD lacks high thermogenic abilities; therefore, it gives exceptional calorie retention for adding bulk muscle.
Epiandrosterone is a natural metabolite of dehydroepiandrosterone (DHEA) via the 5α-reductase enzyme, it may also appear under the name 3b-hydroxy-etioallocholan-17-one. Epiandrosterone is a precursor to Stanolone, a powerful steroid hormone. Epiandrosterone can be found naturally occurring in most mammals and is excreted in urine as a normal part of human metabolism. It provide health benefits such as weight loss, muscle growth, and support immune system function.
Stanolone is the hormone that epiandrosterone converts to in the body and it is very androgenic. This makes hair loss a possible concern with epiandrosterone, but anecdotal evidence has shown that it is not too harsh in this area. Epiandrosterone does not aromatise to estrogen, so bloating and gyno should not be much of a concern. This compound will not produce remarkable size gains in comparison to other prohormones, but it is especially good for strength gains and muscle density and definition, which makes it great to use during a cutting cycle or alongside a prohormone that helps build mass during a bulking phase for a balanced strength and size stack. One additional benefit of epiandrosterone is that it appears to have some immediate neurological effects, so having a dose pre-workout can aid in strength and aggression.
7-keto-DHEA (3-Acetyl-7-Oxo-Dehydroepiandrosterone), also known as 7-oxoprasterone, is a prohormone produced by metabolism of the prohormone dehydroepiandrosterone (DHEA). 7-KETO® DHEA is not directly converted to testosterone or estrogen, and has thus been investigated as a potentially more useful relative of DHEA.
When it comes to fat loss, one way in which cortisol causes problems is by blunting thyroid production. Not only does it lower overall thyroid output, but it inhibits the conversion of T4 to T3 (the more active form of the hormone). The end result is readily apparent in those who have undergone long-term corticosteroid therapy (prednisone, methylprednisone; both are corticosteroids like cortisol), as these patients frequently add bodyfat during treatment. Unfortunately, bodybuilders are exposed to many risk factors for increased cortisol levels, such as weight training, cardio, low-calorie dieting, low-carb dieting, and not getting enough sleep (under 7 hours/night has been shown increase production of this hormone). Even the disconnection of AAS can increase cortisol levels via cortisol rebound. Basically, anything which places stress on the body, either physical or emotional/mental, will cause levels of this hormone to rise.
7-Keto DHEA has been clinically proven to increase T3/T4 levels, as well as the conversion rate of T4 to T3 by directly inhibiting the production of cortisol in the body. It does this by competing with the hydroxysteroid dehydrogenase enzyme (11 b-HSD 1), which is responsible for converting cortisone into cortisol. In laymen’s terms, 7-keto uses up circulating 11 b-HSD 1, thereby leaving less of this enzyme available to initiate the conversion of cortisone to cortisol. However, unlike synthetic thyroid, it doesn’t suppress the hypothalamic pituitary thyroid axis, so natural thyroid production remains unaffected even after discontinuation. This, along with the fact that supplemental 7-Keto has not been shown to have any significant adverse side effects, eliminates the need for off-time/recovery time when using 7-Keto DHEA.
1-DHEA is a naturally occurring DHEA isomer which cannot convert to testosterone or estrogen — but instead converts to the non-estrogenic 1-Testosterone. 1-DHEA gets most of its effects from conversion to 1-androstenediol, which has potent muscle building and hardening effects in and of itself. 1-DHEA does not convert to estrogen nor does it activate the estrogen receptor like DHEA is known to do. It could be referred to as “dry DHEA”. Because of this, it will stack well with other estrogenic steroids such as 4-DHEA to produce† clean gains in muscle tissue.
The strong anabolic properties of 1-testosterone have been established in the literature. Research conducted in the 60’s found that 1-testosterone had a myotrophic (anabolic) potency of 200 as compared to 26 for testosterone, making it over 7 times as anabolic. This was done using the rat levator ani assay, which is commonly used to test the anabolic potency of steroids. In addition to this, 1-testosterone and 1-AD are both unable to aromatize to estrogen. Hence these substances cause very significant increases in muscle size and strength with about the androgenic potential of testosterone and almost no estrogenic side effects (water retention, fat gain, gynecomastia).
5-DHEA has been popular in the life extension crowd since the 1980’s. It’s typically used for its ability to support energy and general well being. More recently, higher doses of 5-DHEA have been used to improve body composition due to DHEA’s mild anabolic and thermogenic effects. This makes 5-DHEA an excellent choice for cutting during a calorie deficient diet, since 5-DHEA has good muscle sparing properties.
5-DHEA converts to testosterone at a rate of about 1%, however it has high conversion to 5-androstenediol, where it gets its mild androgenic and anabolic effects. 5-DHEA’s thermogenic properties come from its conversion to 7-Keto DHEA.
Due to 5-DHEA’s mild androgenic effects it rarely produces hair loss or acne. Although 5-DHEA has moderate estrogenic effects, it rarely produces gyno or undesirable estrogenic side effects. Some more sedentary users have reported anxiety or sleeplessness with DHEA, which is likely related to the neurosteroid activity in the brain. However, this effect is also reported as “motivational energy” which is a frequently reported benefit of 5-DHEA.
Androsta-3 5-diene-7 17-dione is an aromatize inhibiting compound and is a DHEA analog that will reduce estradiol and is mostly used as a post cycle therapy. Androsta-3 5-diene-7 17-dione which helps with decreasing in circulating levels of estrogen in the body. Simply put it will inhibit or reduce the amount of androgens in the body that can convert into estrogen. Androsta-3 5-diene-7 17-dione is a suicide aromatase inhibitor, meaning that it binds to the aromatase enzyme and can not be reversed.
Androsta-3 5-diene-7 17-dione naturally occurs in the human body. In the 1970s, East German steroid chemists, affiliated with the Research Center for Molecular Biology and Medicine, produced Androsta-3 5-diene-7 17-dione in human urine. Later on, in the early ’90s, researchers from the Ohoku College of Pharmacy in Japan were looking for aromatase inhibitors(AIs). They found out that Androsta-3 5-diene-7 17-dione was one of the best AIs available.
Gear Cream Topical Delivery System
- Dimethyl Isosorbide (DMI) – is a high purity solvent and carrier which offers a safe, effective delivery enhancement mechanism for the active ingredients in Gear Cream.
- Ethoxydiglycol – is a cosmetic grade solvent that conforms to the current USP/NF monographs. Ethoxydiglycol is particularly appropriate for skin care preparations where it acts as an excellent solvent and carrier.
- Propylene glycol – is an organic compound that is used 2 primary reasons. First, it has the traits of a humectant; it is able to absorb and help the skin retain moisture. Second, it helps active ingredients penetrate the skin.
- Glycerin – when used on skin works as humectant, which is why it attracts moisture onto your skin.
- Carbomer – helps to distribute and suspend the active ingredients in the Gear Cream.
- Triethanolamine (TEA) – Helps the water-soluble and oil-soluble ingredients blend better. TEA neutralizes fatty acids and solubilizes oils and other ingredients that are not completely soluble in water.
Suggested Use for Gear Cream
For best results apply 1 pump of GEAR Cream twice daily (1 pump in AM & 1 pump in PM) to the upper arms, shoulders/traps, thighs or abdominal areas. Ensure the areas are clean and free from excessive hair, avoid showering or swimming for at least 8 hours after application.